Recent Publications

Click on a link below to see publications for specific lab.


Bubeck-Wardenburg Lab (faculty bio) (research summary)

Inoshima I, Inoshima N, Wilke GA, Powers ME, Frank KM, Wang Y, Bubeck Wardenburg J. A Staphylococcus aureus Pore-Forming Toxin Subverts the Activity of ADAM10 to Cause Lethal Infection. Nature Medicine. 2011 Oct; 17(10):1310-1314.

Powers, M., Kim, H. K., Wang, Y., and Bubeck Wardenburg, J.  ADAM10 mediates vascular injury induced by Staphylococcus aureus a-hemolysin.  J. Infect Dis. 2012, April 2; Epub ahead of print.

Wilke GA, Bubeck Wardenburg J. Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus alpha-hemolysin-mediated cellular injury. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13473-8. Full text.

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Golovkina Lab (faculty bio) (research summary)

Kane M, Case LK, Kopaskie K, Kozlova A, MacDearmid C, Chervonsky AV, Golovkina TV. Successful transmission of a retrovirus depends on the commensal microbiota. Science. 2011 Oct 14;334(6053):245-9. Full text.

Kane M, Case LK, Wang C, Yurkovetskiy L, Dikiy S, Golovkina TV. Innate immune sensing of retroviral infection via Toll-like receptor 7 occurs upon viral entry. Immunity. 2011 Jul 22;35(1):135-45. Epub 2011 Jun 30. Full text.

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Kanabrocki Lab (faculty bio) (research summary)

 Kanabrocki J. Interactions between biocontainment laboratories and their communities: a successful work in progress. Trends Microbiol. 2011 May; 19(5) 209-10. Full text.

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Manicassamy Lab (faculty bio) (research summary)

Manicassamy B, Manicassamy S, Belicha-Villanueva A, Pisanelli G, Pulendran B and García-Sastre. Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus. Proc Natl Acad Sci USA. 2010; 107(25):11531-6. Full Text

Manicassamy B*, Medina-Silva R*, Hai R*, Tsibane T, Stertz S, Nistal-Villán  E,  Palese P, Basler CF and Garcia-Sastre A. Protection of mice against lethal challenge with 2009 H1N1 influenza A virus by 1918-like and classical swineH1N1 based vaccines. PLoS Pathog. 2010 Jan 29;6(1):e1000745. Full Text

Medina RA*, Manicassamy B*, Stertz S*, Seibert CW, Hai R, Belshe RB, Frey SE, Basler CF, Palese P, and García-Sastre A. Pandemic 2009 H1N1 vaccine protects against 1918 Spanish influenza virus. Nature Commun. 2010 Jun 15;1:28. doi: 10.1038/ ncomms1026. Full Text

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Missiakas Lab (faculty bio) (research summary)

Kim HK, Thammavongsa V, Schneewind O, Missiakas D. Recurrent infections and immune evasion strategies of Staphylococcus aureus. Curr Opin Microbiol. 2011 Nov 14. Full text.

Thammavongsa V, Schneewind O, Missiakas DM. Enzymatic properties of Staphylococcus aureus adenosine synthase (AdsA). BMC Biochem. 2011 Oct 28;12:56. Full text.

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Randall Lab (faculty bio) (research summary)

Heaton, N.S., R. Perera, K.L. Berger, S. Khadka, D.J. LaCount, R.J. Kuhn and G. Randall. 2010. Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis. Proc. Natl. Acad. Sci. USA. 107:17345-50.  Full text.

Heaton, N.S. and G. Randall. 2010. Dengue virus induced autophagy regulates lipid metabolism. Cell Host and Microbe. 8:422-32.  Full text.

Berger, K.L., S.M. Kelly, T.X. Jordan, M.A. Tartell and G. Randall. 2011. Hepatitis C virus stimulates the phosphatidylinositol 4-kinase III alpha-dependent phosphatidylinositol 4-phosphate production that is essential for its replication. J. Virol. 85(17):8870-83.  Full text.

Coller, K.E., N.S. Heaton, K.L. Berger, J.D. Cooper, J. Saunders, and G. Randall. 2012. Molecular determinants and dynamics of hepatitis C virus secretion. PLoS Pathogens. 8(1):e1002466. Epub 2012 Jan 5.  Full text.

Oakland, T.E., K.J. Haselton and G. Randall. 2013. EWSR1 binds the hepatitis C virus cis-acting replication element and is required for efficient replication.  J. Virol. 87(12):6625-34.  Full text.

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Roizman Lab (faculty bio) (research summary)

Du, T., Zhou G., and Roizman, B.  HSV-1 gene expression from reactivated ganglia is disordered and concurrent with suppression of latency associated transcript and miRNAS.  Proc. Nat. Acad. Sci. (USA) 108: 18820-18824 2011.  Full text

Zhou, G., Du, T., Roizman B.  The role of CoREST/RET repressor complex in herpes simplex virus 1 productive infection and latency.  Viruses, 5:1208-1218; doi:10.3390/v5051208, 2013 PMID: 23628827.  Full text

Du, T., Zhou, G. and Roizman, B.  Modulation of reactivation of latent herpes simplex virus 1 in ganglionic organ cultures by p300/CBP and STAT3.  Proc.  Natl. Acad. Sci. (U S A). E2621, 2013 [Epub ahead of print June 20, 2013] PMID: 23788661. Full text

Kalamvoki, M  and Roizman, B..  HSV-1 degrades, stabilizes, requires, or is stung by STING depending on ICP0, the US3 protein kinase and cell derivation. Proc. Nat. Acad. Sci.  (USA) 2014; 111:E611-E617, February 3, 2014 (10.1073/pnas.1323414111). Originally published at on Jan 21 2014  Full text

Kalamvoki M Du T. and Roizman B.  Cells infected with herpes simplex virus 1 export to uninfected cells exospores containing STING, viral mRNAs, and micro RNAs. Proc. Nat. Acad. of Sci.  USA. 111:E4991-E4996, November 18, 2014 (10.1073/pnas.1419338111).  Full text

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Schneewind Lab (faculty bio) (research summary)

McAdow M, Kim HK, Dedent AC, Hendrickx AP, Schneewind O, Missiakas DM. Preventing Staphylococcus aureus Sepsis through the Inhibition of Its Agglutination in Blood. PLoS Pathog. 2011 Oct;7(10):e1002307. Full text.

Frankel MB, Hendrickx AP, Missiakas DM, Schneewind O. LytN, a murein hydrolase in the cross-wall compartment of Staphylococcus aureus, is involved in proper bacterial growth and envelope assembly. J Biol Chem. 2011 Sep 16;286(37):32593-605. Full text.

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Shuman Lab (faculty bio) (research summary)

Franco IS, Shohdy N, Shuman HA. The Legionella pneumophila effector VipA is an actin nucleator that alters host cell organelle trafficking. PLoS Pathog. 2012 Feb;8(2):e1002546. Epub 2012 Feb 23.

Amaro F, Gilbert JA, Owens S, Trimble W, Shuman HA. Whole-genome sequence of the human pathogen Legionella pneumophila serogroup 12 strain 570-CO-H. J Bacteriol. 2012 Mar;194(6):1613-4.

Levi A, Folcher M, Jenal U, Shuman HA. Cyclic diguanylate signaling proteins control intracellular growth of Legionella pneumophila. MBio. 2011 Jan 11;2(1):e00316-10. Full text.

Faucher SP, Friedlander G, Livny J, Margalit H, Shuman HA. Legionella Pneumophila Transcriptome during Intracellular Multiplication in Human Macrophages. Front Microbiol. 2011;2:60. Full text.

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