Dominique Missiakas, PhD

Dr. Missiakas’s research program examines the Gram-positive pathogens Staphylococcus aureus and Bacillus anthracis. This program seeks to appreciate the biogenesis of the envelope of these microorganisms as well as the secretion of their virulence factors and host pathways targeted by these pathogens.

Université of Paris XI
Orsay, France
Ph.D. - Biochemistry
1991

Protein coopted from a phage restriction system dictates orthogonal cell division plane selection in Staphylococcus aureus.
Protein coopted from a phage restriction system dictates orthogonal cell division plane selection in Staphylococcus aureus. bioRxiv. 2023 Sep 03.
PMID: 37886572

A humanized monoclonal antibody targeting protein a promotes opsonophagocytosis of Staphylococcus aureus in human umbilical cord blood.
A humanized monoclonal antibody targeting protein a promotes opsonophagocytosis of Staphylococcus aureus in human umbilical cord blood. Vaccine. 2023 08 07; 41(35):5079-5084.
PMID: 37455161

Intranasal soluble ACE2 improves survival and prevents brain SARS-CoV-2 infection.
Intranasal soluble ACE2 improves survival and prevents brain SARS-CoV-2 infection. Life Sci Alliance. 2023 07; 6(7).
PMID: 37041017

The Type 7b Secretion System of S. aureus and Its Role in Colonization and Systemic Infection.
The Type 7b Secretion System of S. aureus and Its Role in Colonization and Systemic Infection. Infect Immun. 2023 05 16; 91(5):e0001523.
PMID: 37039657

Reply to Barton et al: signatures of natural selection during the Black Death.
Reply to Barton et al: signatures of natural selection during the Black Death. bioRxiv. 2023 Apr 07.
PMID: 37066254

Immunoglobulin G subclasses confer protection against Staphylococcus aureus bloodstream dissemination through distinct mechanisms in mouse models.
Immunoglobulin G subclasses confer protection against Staphylococcus aureus bloodstream dissemination through distinct mechanisms in mouse models. Proc Natl Acad Sci U S A. 2023 04 04; 120(14):e2220765120.
PMID: 36972444

Modeling gastrointestinal anthrax disease.
Modeling gastrointestinal anthrax disease. Res Microbiol. 2023 Jul-Aug; 174(6):104026.
PMID: 36646261

Neutrophils Protect Against Staphylococcus aureus Endocarditis Progression Independent of Extracellular Trap Release.
Neutrophils Protect Against Staphylococcus aureus Endocarditis Progression Independent of Extracellular Trap Release. Arterioscler Thromb Vasc Biol. 2023 02; 43(2):267-285.
PMID: 36453281

Evolution of immune genes is associated with the Black Death.
Evolution of immune genes is associated with the Black Death. Nature. 2022 Nov; 611(7935):312-319.
PMID: 36261521

Contribution of TagA-Like Glycosyltransferases to the Assembly of the Secondary Cell Wall Polysaccharide in Bacillus anthracis.
Contribution of TagA-Like Glycosyltransferases to the Assembly of the Secondary Cell Wall Polysaccharide in Bacillus anthracis. J Bacteriol. 2022 Sep 20; 204(9):e0025322.
PMID: 35997505

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