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Erin Green, PhD

Nosocomial infections are an emerging public health threat and frequently occur as a result of patient contact with bacteria persisting on hospital surfaces in a desiccated state. We are interested in discovering novel mechanisms by which bacterial pathogens sense and adapt to long-term desiccation stress, as well as the regulatory mechanisms involved in mediating the transition between environmental reservoirs and mammalian hosts, with a particular focus on the emerging multidrug resistant pathogen, Acinetobacter baumannii. Additionally, we are interested in studying mechanisms by which A. baumannii controls turnover of its protein content in response to changing environmental conditions via regulated proteolysis by AAA+ family proteases.