Microbes exhibit variable forms of cellular metabolism, the distinctive properties of which reflect critical features of relevant microbial ecosystems. In the context of the gut microbiota, these metabolic processes generate numerous small molecules that influence host biology in a myriad of ways. Our research seeks to develop a fundamental understanding of the relationship between microbial metabolism and healthy/diseased states of the gut microbiota and, eventually, to exploit these insights in the development of targeted therapies.
University of California
Berkeley
Postdoctoral Fellow
2019
Northwestern University
Postdoctoral Associate
2016
Northwestern University
PhD
2013
Bard College
BA
2008
Microbiome histidine competition mediates dietary control of systemic imidazole propionate.
Microbiome histidine competition mediates dietary control of systemic imidazole propionate. bioRxiv. 2026 Jun 23.
PMID: 42395374
The intestinal microbiota impacts nutritional immunity and resistance to Acinetobacter baumannii pneumonia.
The intestinal microbiota impacts nutritional immunity and resistance to Acinetobacter baumannii pneumonia. Proc Natl Acad Sci U S A. 2026 Apr 28; 123(17):e2534432123.
PMID: 42012958
Gut bacteria metabolize natural and synthetic steroid hormones via the reductive OsrABC pathway.
Gut bacteria metabolize natural and synthetic steroid hormones via the reductive OsrABC pathway. Cell Host Microbe. 2025 11 12; 33(11):1873-1885.e7.
PMID: 41118772
DNA-utilization loci enable exogenous DNA metabolism in gut Bacteroidales.
DNA-utilization loci enable exogenous DNA metabolism in gut Bacteroidales. Proc Natl Acad Sci U S A. 2025 Sep 23; 122(38):e2505388122.
PMID: 40956896
Gut Bacteria Metabolize Natural and Synthetic Steroid Hormones via the Reductive OsrABC Pathway.
Gut Bacteria Metabolize Natural and Synthetic Steroid Hormones via the Reductive OsrABC Pathway. bioRxiv. 2025 Sep 09.
PMID: 39416003
Author Correction: Dietary- and host-derived metabolites are used by diverse gut bacteria for anaerobic respiration.
Author Correction: Dietary- and host-derived metabolites are used by diverse gut bacteria for anaerobic respiration. Nat Microbiol. 2025 Jun; 10(6):1550.
PMID: 40379934
Quantitative insights into the efficacy of genome-resolved surveys of microbial communities through ribosomal protein phylogeography and EcoPhylo.
Quantitative insights into the efficacy of genome-resolved surveys of microbial communities through ribosomal protein phylogeography and EcoPhylo. bioRxiv. 2025 Apr 23.
PMID: 39868213
Gut Bacteria Metabolize Natural and Synthetic Steroid Hormones via the Reductive OsrABC Pathway.
Gut Bacteria Metabolize Natural and Synthetic Steroid Hormones via the Reductive OsrABC Pathway. bioRxiv. 2024 Oct 09.
PMID: 39416003
Regulation of immune responses to food by commensal microbes.
Regulation of immune responses to food by commensal microbes. Immunol Rev. 2024 09; 326(1):203-218.
PMID: 39285525
Versatile roles of protein flavinylation in bacterial extracyotosolic electron transfer.
Versatile roles of protein flavinylation in bacterial extracyotosolic electron transfer. mSystems. 2024 08 20; 9(8):e0037524.
PMID: 39041811